1. Oliveira C, Pinheiro H, Figueiredo J, Seruca R, Carneiro F

Familial gastric cancer: genetic susceptibility, pathology, and implications for management. The Lancet. Oncology 16: e60-e70, 2015.  [Review] 

 doi: 10.1016/S1470-2045(14)71016-2 PMID: 25638682.

 

2. Oliveira C, Sousa S, Pinheiro H, Karam R, Bordeira-Carriço R, Senz J, Kaurah P, Carvalho J, Pereira R, Gusmão L, Wen X, Cipriano MA, Yokota J, Carneiro F, Huntsman D, Seruca R

Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression. Gastroenterology 136: 2137-48, 2009.  [Article] 

 doi: 10.1053/j.gastro.2009.02.065 PMID: 19269290.

 

3. Paredes J, Figueiredo J, Albergaria A, Oliveira P, Carvalho J, Ribeiro AS, Caldeira J, Costa AM, Simões-Correia J, Oliveira MJ, Pinheiro H, Pinho SS, Mateus R, Reis CA, Leite M, Fernandes MS, Schmitt F, Carneiro F, Figueiredo C, Oliveira C, Seruca R

Epithelial E- and P-cadherins: Role and clinical significance in cancer. Biochimica et Biophysica acta-Reviews on Cancer 1826: 297-311, 2012.  [Review] 

 doi: 10.1016/j.bbcan.2012.05.002 PMID: 22613680.

 

4. Pinheiro H, Bordeira-Carriço R, Seixas S, Carvalho J, Senz J, Oliveira P, Inácio P, Gusmão L, Rocha J, Huntsman D, Seruca R, Oliveira C

Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer. Human molecular genetics 19: 943-52, 2010.  [Article] 

 doi: 10.1093/hmg/ddp537. PMID: 19965908.

 

5. Pinheiro H, Carvalho J, Oliveira P, Ferreira D, Pinto MT, Osório H, Licastro D, Bordeira-Carriço R, Jordan P, Lazarevic D, Sanges R, Stupka E, Huntsman D, Seruca R, Oliveira C

Transcription initiation arising from E-cadherin/CDH1 intron2: a novel protein isoform that increases gastric cancer cell invasion and angiogenesis. Human molecular genetics 21: 4253-69, 2012.  [Article] 

 doi: 10.1093/hmg/dds248 PMID: 22752307.

 

6. Gaston D, Hansford S, Oliveira C, Nightingale M, Pinheiro H, Macgillivray C, Kaurah P, Rideout AL, Steele P, Soares G, Huang WY, Whitehouse S, Blowers S, LeBlanc MA, Jiang H, Greer W, Samuels ME, Orr A, Fernandez CV, Majewski J, Ludman M, Dyack S, Penney LS, McMaster CR, Huntsman D, Bedard K

Germline mutations in MAP3K6 are associated with familial gastric cancer. PLoS genetics 10: e1004669, 2014.  [Article] 

 doi: 10.1371/journal.pgen.1004669 PMID: 25340522.

 

7. Oliveira C, Senz J, Kaurah P, Pinheiro H, Sanges R, Haegert A, Corso G, Schouten J, Fitzgerald R, Vogelsang H, Keller G, Dwerryhouse S, Grimmer D, Chin SF, Yang HK, Jackson CE, Seruca R, Roviello F, Stupka E, Caldas C, Huntsman D

Germline CDH1 deletions in hereditary diffuse gastric cancer families. Human molecular genetics 18: 1545-55, 2009.  [Article] 

 doi: 10.1093/hmg/ddp046 PMID: 19168852.

 

8. van der Post RS, Vogelaar IP, Carneiro F, Guilford P, Huntsman D, Hoogerbrugge N, Caldas C, Schreiber KE, Hardwick RH, Ausems MG, Bardram L, Benusiglio PR, Bisseling TM, Blair V, Bleiker E, Boussioutas A, Cats A, Coit D, DeGregorio L, Figueiredo J, Ford JM, Heijkoop E, Hermens R, Humar B, Kaurah P, Keller G, Lai J, Ligtenberg MJ, O'Donovan M, Oliveira C, Pinheiro H, Ragunath K, Rasenberg E, Richardson S, Roviello F, Schackert H, Seruca R, Taylor A, Ter Huurne A, Tischkowitz M, Joe ST, van Dijck B, van Grieken NC, van Hillegersberg R, van Sandick JW, Vehof R, van Krieken JH, Fitzgerald RC

Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers. Journal of medical genetics 52: 361-374, 2015.  [Review] 

 doi: 10.1136/jmedgenet-2015-103094 PMID: 25979631.

 

9. Corso G, Velho S, Paredes J, Pedrazzani C, Martins D, Milanezi F, Pascale V, Vindigni C, Pinheiro H, Leite M, Marrelli D, Sousa S, Carneiro F, Oliveira C, Roviello F, Seruca R

Oncogenic mutations in gastric cancer with microsatellite instability. European journal of cancer (Oxford, England : 1990) 47: 443-51, 2011.  [Article] 

 doi: 10.1016/j.ejca.2010.09.008 PMID: 20937558.

 

10. Corso G, Pedrazzani C, Pinheiro H, Fernandes E, Marrelli D, Rinnovati A, Pascale V, Seruca R, Oliveira C, Roviello F

E-cadherin genetic screening and clinico-pathologic characteristics of early onset gastric cancer. European journal of cancer (Oxford, England : 1990) 47: 631-9, 2011.  [Article] 

 doi: 10.1016/j.ejca.2010.10.011 PMID: 21106365.

 

11. Masciari S, Larsson N, Senz J, Boyd N, Kaurah P, Kandel MJ, Harris LN, Pinheiro HC, Troussard A, Miron P, Tung N, Oliveira C, Collins L, Schnitt S, Garber JE, Huntsman D

Germline E-cadherin mutations in familial lobular breast cancer. Journal of medical genetics 44: 726-31, 2007.  [Article] 

 doi: 10.1136/jmg.2007.051268 PMID: 17660459.

 

12. Bordeira-Carriço R, Ferreira D, Mateus DD, Pinheiro H, Pêgo AP, Santos MA, Oliveira C

Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA. European journal of human genetics : EJHG 22: 1085-92, 2014.  [Article] 

 doi: 10.1038/ejhg.2013.292 PMID: 24424122.

 

13. Vogelaar IP, van der Post RS, van Krieken JHJ, Spruijt L, van Zelst-Stams WA, Kets CM, Lubinski J, Jakubowska A, Teodorczyk U, Aalfs CM, van Hest LP, Pinheiro H, Oliveira C, Jhangiani SN, Muzny DM, Gibbs RA, Lupski JR, de Ligt J, Vissers LELM, Hoischen A, Gilissen C, van de Vorst M, Goeman JJ, Schackert HK, Ranzani GN, Molinaro V, Gómez García EB, Hes FJ, Holinski-Feder E, Genuardi M, Ausems MGEM, Sijmons RH, Wagner A, van der Kolk LE, Bjørnevoll I, Høberg-Vetti H, van Kessel AG, Kuiper RP, Ligtenberg MJL, Hoogerbrugge N

Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing. European journal of human genetics : EJHG 25: 1246-1252, 2017.  [Article] 

 doi: 10.1038/ejhg.2017.138 PMID: 28875981.

 

14. Carneiro P, Fernandes MS, Figueiredo J, Caldeira J, Carvalho J, Pinheiro H, Leite M, Melo S, Oliveira P, Simões-Correia J, Oliveira MJ, Carneiro F, Figueiredo C, Paredes J, Oliveira C, Seruca R

E-cadherin dysfunction in gastric cancer - Cellular consequences, clinical applications and open questions. FEBS letters 586: 2981-9, 2012.  [Review] 

 doi: 10.1016/j.febslet.2012.07.045 PMID: 22841718.

 

15. Pinheiro H, Oliveira C, Seruca R, Carneiro F

Hereditary diffuse gastric cancer - Pathophysiology and clinical management. Best practice & research. Clinical gastroenterology 28: 1055-1068, 2014.  [Article] 

 doi: 10.1016/j.bpg.2014.09.007 PMID: 25439071.

 

16. Gonçalves CM, Castro MA, Henriques T, Oliveira MI, Pinheiro HC, Oliveira C, Sreenu VB, Evans EJ, Davis SJ, Moreira A, Carmo AM

Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Molecular immunology 46: 2585-96, 2009.  [Article] 

 doi: 10.1016/j.molimm.2009.05.006 PMID: 19535143.

 

17. Oliveira C, Pinheiro H, Figueiredo J, Seruca R, Carneiro F

E-cadherin alterations in hereditary disorders with emphasis on hereditary diffuse gastric cancer. Progress in molecular biology and translational science 116: 337-59, 2013.  [Review; Book Chapter] 

 doi: 10.1016/B978-0-12-394311-8.00015-7 PMID: 23481202.

 

18. Pinheiro HC, Carrico R, Carvalho J, Oliveira P, Gusmao L, Seixas S, Rocha J, Huntsman D, Seruca R, Oliveira C

Allele-Specific CDH1 Downregulation Increases Susceptibility to Diffuse Gastric Cancer Helicobacter 14: 381-381, 2009.  [Meeting Abstract] 

.

 

19. Oliveira C, Sousa S, Pinheiro H, Bordeira-Carrico R, Carvalho J, Carneiro F, Huntsman D, Seruca R

Quantification of Epigenetic and Genetic Second Hits in CDH1 During Hereditary Diffuse Gastric Cancer Syndrome Progression Helicobacter 14: 383-383, 2009.  [Meeting Abstract] 

.

 

20. Corso G, Sousa S, Pedrazzani C, Marrelli D, Carvalho J, Pinheiro H, Seruca R, Roviello F, Oliveira C

Systematic Study of CDH1 Inactivation in Human Gastric Cancer Helicobacter 14: 330-330, 2009.  [Meeting Abstract] 

.

 

21. Queirós P, Pinheiro H, Carvalho J, Oliveira P, Gullo I, Carneiro F, Almeida GM, Oliveira C

KRAS mutations in microsatellite instable gastric tumours: impact of targeted treatment and intratumoural heterogeneity. Virchows Archiv : an international journal of pathology 467: 383-92, 2015.  [Article] 

 doi: 10.1007/s00428-015-1823-7 PMID: 26318594.

 

22. Hansford S, Kaurah P, Li-Chang H, Woo M, Senz J, Pinheiro H, schrader K, Schaeffer DF, Shumansky K, Zogopoulos G, Almeida Santos T, Claro I, Carvalho J, Nielsen C, Padilla S, Lum A, Talhouk A, Baker-Lange K, Richardson S, Lewis I, Lindor N, Pennell E, MacMillan A, Fernandez B, Keller G, Lynch H, Shah S, Guilford P, Gallinger S, Corso G, Roviello F, Caldas C, Oliveira C, Pharoah P, Huntsman D

Hereditary Diffuse Gastric Cancer Syndrome CDH1 Mutations and Beyond JAMA Oncology  1, 2014.  [Article] 

 doi: 10.1001/jamaoncol.2014.168.

 

23. Pinheiro H, Oliveira P, Oliveira C

Hereditary cancer risk assessment: challenges for the next-gen sequencing era. Frontiers in oncology 5: 62, 2015.  [Editorial Material] 

 doi: 10.3389/fonc.2015.00062 PMID: 25853090.