1. Marcos NT, Magalhães A, Ferreira B, Oliveira MJ, Carvalho AS, Mendes N, Gilmartin T, Head SR, Figueiredo C, David L, Santos-Silva F, Reis CA

Helicobacter pylori induces beta3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x. The Journal of clinical investigation 118: 2325-36, 2008.  [Article] 

 doi: 10.1172/JCI34324 PMID: 18483624.

 

2. Rei M, Freitas R, Sousa A, Caffrey T, Hollingsworth MA, Santos-Silva F

Characterization of MUC1 signaling pathways in pancreatic cancer stem cells. Gastroenterology  138, 2010.  [] 

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3. Marcos NT, Pinho S, Grandela C, Cruz A, Samyn-Petit B, Harduin-Lepers A, Almeida R, Silva F, Morais V, Costa J, Kihlberg J, Clausen H, Reis CA

Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen. Cancer research 64: 7050-7, 2004.  [Article] 

 doi: 10.1158/0008-5472.CAN-04-1921 PMID: 15466199.

 

4. Mesquita P, Jonckheere N, Almeida R, Ducourouble MP, Serpa J, Silva E, Pigny P, Silva FS, Reis C, Silberg D, Van Seuningen I, David L

Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines. The Journal of biological chemistry 278: 51549-56, 2003.  [Article] 

 doi: 10.1074/jbc.M309019200 PMID: 14525978.

 

5. Almeida R, Almeida J, Shoshkes M, Mendes N, Mesquita P, Silva E, Van Seuningen I, Reis CA, Santos-Silva F, David L

OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells. The Journal of pathology 207: 396-401, 2005.  [Article] 

 doi: 10.1002/path.1861 PMID: 16278805.

 

6. Coelho SC, Almeida GM, Pereira MC, Santos-Silva F, Coelho MA

Functionalized gold nanoparticles improve afatinib delivery into cancer cells. Expert opinion on drug delivery 13: 133-41, 2016.  [Article] 

 doi: 10.1517/17425247.2015.1083973 PMID: 26371512.

 

7. Coelho SC, Almeida GM, Santos-Silva F, Pereira MC, Coelho MA

Enhancing the efficiency of bortezomib conjugated to pegylated gold nanoparticles: an in vitro study on human pancreatic cancer cells and adenocarcinoma human lung alveolar basal epithelial cells. Expert opinion on drug delivery 13: 1075-81, 2016.  [Article] 

 doi: 10.1080/17425247.2016.1178234 PMID: 27087021.

 

8. Barros R, Pereira B, Duluc I, Azevedo M, Mendes N, Camilo V, Jacobs RJ, Paulo P, Santos-Silva F, van Seuningen I, van den Brink GR, David L, Freund JN, Almeida R

Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines. The Journal of pathology 215: 411-20, 2008.  [Article] 

 doi: 10.1002/path.2369 PMID: 18498120.

 

9. Freitas DP, Teixeira CA, Santos-Silva F, Vasconcelos MH, Almeida GM

Therapy-induced enrichment of putative lung cancer stem-like cells. International journal of cancer 134: 1270-8, 2014.  [Review] 

 doi: 10.1002/ijc.28478 PMID: 24105655.

 

10. Almeida R, Silva E, Santos-Silva F, Silberg DG, Wang J, De Bolós C, David L

Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas. The Journal of pathology 199: 36-40, 2003.  [Article] 

 doi: 10.1002/path.1246 PMID: 12474224.

 

11. David L, Silva F, Seruca R, Pinto M, Reis C, Sobrinho-Simões M

Correspondence re: A. E. Biemer-Huttmann et al., Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clin. Cancer Res., 6: 1909-1916, 2000. Clinical cancer research : an official journal of the American Association for Cancer Research 6: 4461-2, 2000.  [Letter] 

 PMID: 11106267.

 

12. Coelho SC, Rocha S, Juzenas P, Sampaio P, Almeida GM, Silva FS, Pereira MC, Coelho MA

Gold nanoparticle delivery-enhanced proteasome inhibitor effect in adenocarcinoma cells. Expert opinion on drug delivery 10: 1345-52, 2013.  [Article] 

 doi: 10.1517/17425247.2013.827659 PMID: 23937147.

 

13. Costa N, Paulo P, Caffrey T, Hollingsworth MA, Santos-Silva F

Impact of MUC1 mucin downregulation in the phenotypic characteristics of MKN45 gastric carcinoma cell line PloS one  1, 2011.  [Article] 

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14. R Costa N, Sousa A, Teixeira C, Caffrey T, A Hollingsworth M, Santos Silva F

MUC1 mucin conditions MAPK signaling pathway in MKN45 gastric carcinoma cells PloS one  1, 2012.  [] 

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15. Silva F, Carvalho F, Peixoto A, Teixeira A, Almeida R, Reis C, Bravo LE, Realpe L, Correa P, David L

MUC1 polymorphism confers increased risk for intestinal metaplasia in a Colombian population with chronic gastritis. European journal of human genetics : EJHG 11: 380-4, 2003.  [Article] 

 doi: 10.1038/sj.ejhg.5200978 PMID: 12734543.

 

16. Schmitt FC, Soares R, Gobbi H, Milanezzi F, Santos-Silva F, Cirnes L, Costa C, Seruca R

Microsatellite instability in medullary breast carcinomas. International journal of cancer 82: 644-7, 1999.  [Article] 

 PMID: 10417760.

 

17. Santos-Silva F, Fonseca A, Caffrey T, Carvalho F, Mesquita P, Reis C, Almeida R, David L, Hollingsworth MA

Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism. Glycobiology 15: 511-7, 2005.  [Article] 

 doi: 10.1093/glycob/cwi027 PMID: 15604091.

 

18. Pinho S, Marcos NT, Ferreira B, Carvalho AS, Oliveira MJ, Santos-Silva F, Harduin-Lepers A, Reis CA

Biological significance of cancer-associated sialyl-Tn antigen: modulation of malignant phenotype in gastric carcinoma cells. Cancer letters 249: 157-70, 2007.  [Article] 

 doi: 10.1016/j.canlet.2006.08.010 PMID: 16965854.

 

19. Mesquita P, Raquel A, Nuno L, Reis CA, Silva LF, Serpa J, Van Seuningen I, Barros H, David L

Metaplasia--a transdifferentiation process that facilitates cancer development: the model of gastric intestinal metaplasia. Critical reviews in oncogenesis 12: 3-26, 2006.  [] 

 PMID: 17078204.

 

20. Peleteiro B, Lunet N, Santos-Silva F, David L, Figueiredo C, Barros H

Short mucin 1 alleles are associated with low virulent H pylori strains infection. World journal of gastroenterology 13: 1885-6, 2007.  [Letter] 

 PMID: 17465489.

 

21. Serpa J, Mesquita P, Mendes N, Oliveira C, Almeida R, Santos-Silva F, Reis CA, LePendu J, David L

Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation. Cancer letters 242: 191-7, 2006.  [Article] 

 doi: 10.1016/j.canlet.2005.11.009 PMID: 16427187.

 

22. Frasco MF, Almeida GM, Santos-Silva F, Pereira Mdo C, Coelho MA

Transferrin surface-modified PLGA nanoparticles-mediated delivery of a proteasome inhibitor to human pancreatic cancer cells. Journal of biomedical materials research. Part A 103: 1476-84, 2015.  [Article] 

 doi: 10.1002/jbm.a.35286 PMID: 25046528.

 

23. Barros A, Moreira L, Santos H, Ribeiro N, Carvalho L, Santos-Silva F

"Cancer - educate to prevent" - high-school teachers, the new promoters of cancer prevention education campaigns. PloS one 9: e96672, 2014.  [Article] 

 doi: 10.1371/journal.pone.0096672 PMID: 24817168.

 

24. Ribeiro N, Moreira L, Barros A, Almeida AM, Santos Silva F

Guidelines for a Cancer Prevention Smartphone Application: a mixed-methods study International Journal of Medical informatics  1, 2016.  [Article] 

 doi: 10.1016/j.ijmedinf.2016.07.007.

 

25. Alves C, Silva F, Gusmão L, Seruca R, Soares P, Reis RM, Amorim A

Extended structural variation of a pentanucleotide repeat in the GSTP1 gene: characterisation in a normal population and in thyroid and gastric tumours. European journal of human genetics : EJHG 8: 540-4, 2000.  [Article] 

 doi: 10.1038/sj.ejhg.5200486 PMID: 10909855.

 

26. Silva F, Carvalho F, Peixoto A, Seixas M, Almeida R, Carneiro F, Mesquita P, Figueiredo C, Nogueira C, Swallow DM, Amorim A, David L

MUC1 gene polymorphism in the gastric carcinogenesis pathway. European journal of human genetics : EJHG 9: 548-52, 2001.  [Article] 

 doi: 10.1038/sj.ejhg.5200677 PMID: 11464247.

 

27. Ribeiro N, Moreira L, Almeida AMP, Santos-Silva F

Pilot study of a smartphone-based intervention to promote cancer prevention behaviours. International journal of medical informatics 108: 125-133, 2017.  [Article] 

 doi: 10.1016/j.ijmedinf.2017.10.013 PMID: 29132617.

 

28. Pinto-de-Sousa J, Silva F, David L, Leitão D, Seixas M, Pimenta A, Cardoso-de-Oliveira M

Clinicopathological significance and survival influence of p53 protein expression in gastric carcinoma. Histopathology 44: 323-31, 2004.  [Article] 

 doi: 10.1111/j.1365-2559.2004.01852.x PMID: 15049897.

 

29. Marcos NT, Magalhães A, Ferreira B, Oliveira M, Mendes N, Gilmartin T, Head S, Carvalho AS, Figueiredo C, David L, Santos-Silva F, Reis CA

H. pylori Induces beta 3GlcNAc-T5 in Gastric Epithelial Cells Leading to Expression of Sialyl-Lewis X, the Ligand for SabA Adhesin Helicobacter 14: 371, 2009.  [Meeting Abstract] 

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30. Costa NR, Caffrey T, Hollingsworth M, Santos-Silva F

MUC1 Mucin-Mediated Signaling Pathways in Gastric Carcinoma Cells Helicobacter 14: 384-384, 2009.  [Meeting Abstract] 

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31. Mesquita P, Peixoto AJ, Seruca R, Hanski C, Almeida R, Silva F, Reis C, David L

Role of site-specific promoter hypomethylation in aberrant MUC2 mucin expression in mucinous gastric carcinomas. Cancer letters 189: 129-36, 2003.  [Article] 

 PMID: 12490305.

 

32. Marcos NT, Cruz A, Silva F, Almeida R, David L, Mandel U, Clausen H, Von Mensdorff-Pouilly S, Reis CA

Polypeptide GalNAc-transferases, ST6GalNAc-transferase I, and ST3Gal-transferase I expression in gastric carcinoma cell lines. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 51: 761-71, 2003.  [Article] 

 PMID: 12754287.

 

33. Serpa J, Almeida R, Oliveira C, Silva FS, Silva E, Reis C, Le Pendu J, Oliveira G, Ribeiro LM, David L

Lewis enzyme (alpha1-3/4 fucosyltransferase) polymorphisms do not explain the Lewis phenotype in the gastric mucosa of a Portuguese population. Journal of human genetics 48: 183-9, 2003.  [Article] 

 doi: 10.1007/s10038-003-0007-5 PMID: 12730721.

 

34. Costa NR, Mendes N, Marcos NT, Reis CA, Caffrey T, Hollingsworth MA, Santos-Silva F

Relevance of MUC1 mucin variable number of tandem repeats polymorphism in H pylori adhesion to gastric epithelial cells. World journal of gastroenterology 14: 1411-4, 2008.  [Article] 

 PMID: 18322957.

 

35. David L, Teixeira A, Reis C, Peixoto A, Carvalho F, Silva F, Sobrinho-Simões M

Gene-environment interactions in the stomach: role of mucins in Helicobacter pylori adhesion to normal and metaplastic mucosa of the stomach. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 1: 103, 2001.  [Article; Proceedings Paper] 

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36. Ribeiro N, Moreira L, Almeida AMP, Santos-Silva F

Can Smartphones Promote Cancer Prevention Behaviours in Healthy Young Adults? A Prospective Study. Journal of cancer education : the official journal of the American Association for Cancer Education 34: 847-853, 2019.  [Article] 

 doi: 10.1007/s13187-018-1382-0 PMID: 29931456.

 

37. Barros A, Moreira L, Santos H, Ribeiro N, Santos-Silva F

Development of a Measurement Tool to Assess Students' Knowledge and Perceptions About Cancer (SKPaC). Journal of cancer education : the official journal of the American Association for Cancer Education 34: 556-561, 2019.  [Article] 

 doi: 10.1007/s13187-018-1341-9 PMID: 29508229.

 

38. Barros A, Santos H, Moreira L, Ribeiro N, Silva L, Santos-Silva F

Correction to: The Cancer, Educate to Prevent Model-the Potential of School Environment for Primary Prevention of Cancer. Journal of cancer education : the official journal of the American Association for Cancer Education 33: 497, 2018.  [Correction] 

 doi: 10.1007/s13187-018-1327-7 PMID: 29376205.

 

39. Barros A, Santos H, Moreira L, Ribeiro N, Silva L, Santos-Silva F

The Cancer, Educate to Prevent Model-the Potential of School Environment for Primary Prevention of Cancer. Journal of cancer education : the official journal of the American Association for Cancer Education 31: 646-651, 2016.  [Article] 

 doi: 10.1007/s13187-015-0892-2 PMID: 26268942.

 

40. Barros A, Moreira L, Santos H, Ribeiro N, Carvalho L, Santos-Silva F

“Cancer, educate to prevent” – Can high-school teachers be the cornerstone of a new cancer prevention education? Journal of Cancer Education  1, 2014.  [] 

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41. Ribeiro N, Moreira L, Almeida AM, Santos Silva F

Happy: Cancer Prevention Using Smartphones Procedia Computer Science 100: 466-473, 2016.  [Proceedings Paper] 

 doi: 10.1016/j.procs.2016.09.183.

 

42. Gusmão L, Prata MJ, Amorim A, Silva F, Bessa I

Characterization of four short tandem repeat loci (THO1, VWA31/A, CD4, and TP53) in northern Portugal. Human biology; an international record of research 69: 31-40, 1997.  [Article] 

 PMID: 9037893.

 

43. Silva F, Gusmão L, Alves C, Seruca R, David L, Amorim A

Tetra- and pentanucleotide short tandem repeat instability in gastric cancer. Electrophoresis 18: 1633-6, 1997.  [Article; Proceedings Paper] 

 doi: 10.1002/elps.1150180926 PMID: 9378135.

 

44. Constância M, Seruca R, Carneiro F, Silva F, Castedo S

Retinoblastoma gene structure and product expression in human gastric carcinomas. British journal of cancer 70: 1018-24, 1994.  [Article] 

 PMID: 7947078.

 

45. Silva F, Gusmão L, Amorim A

Segregation analysis of tetra- and pentanucleotide short tandem repeat polymorphisms: deviation from Mendelian expectations. Electrophoresis 20: 1697-701, 1999.  [Article; Proceedings Paper] 

 doi: 10.1002/(SICI)1522-2683(19990101)20:8<1697::AID-ELPS1697>3.0.CO;2-3 PMID: 10435433.

 

46. Ribeiro N, Moreira L, Pisco Almeida AM, Santos-Silva F

Mobile Seamless Learning Tool for Cancer Education Smart Innovation, Systems and Technologies 80: 3-10, 2017.  [] 

 doi: 10.1007/978-3-319-61322-2_1.

 

47. Costa N, Sousa A, Teixeira C, Castro J, Guimarães N, Santos-Silva F

Oncogenic signaling in gastric cancer IntechOpen  1, 2011.  [] 

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48. Silva F, Amorim A, Gusmão L

Somatic instability in gastric tumors at STRs used in forensic genetics. Progression in Forensic Genetics 7  424-426, 1998.  [Proceedings Paper] 

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49. Ribeiro N, Moreira L, Almeida A M, Santos Silva L F

Smartphones: Innovative Tools in Cancer Prevention Encyclopedia of E-Health and Telemedicine  1, 2016.  [] 

 doi: 10.4018/978-1-4666-9978-6.ch081.